Uit de medische media

[oma]

Nieuwe definitie Sepsis. Wat mij betreft kan het ongezien de vuilnisbak in.

The Society of Critical Care Medicine (SCCM)  and the European Society of Intensive Care Medicine (ESICM) redefined sepsis with the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).

http://foamcast.org/2016/02/21/sepsis-redefined/

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Special Communication | February 23, 2016
CARING FOR THE CRITICALLY ILL PATIENT
The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3) FREE
Mervyn Singer, MD, FRCP1; Clifford S. Deutschman, MD, MS2; Christopher Warren Seymour, MD, MSc3; Manu Shankar-Hari, MSc, MD, FFICM4; Djillali Annane, MD, PhD5; Michael Bauer, MD6; Rinaldo Bellomo, MD7; Gordon R. Bernard, MD8; Jean-Daniel Chiche, MD, PhD9; Craig M. Coopersmith, MD10; Richard S. Hotchkiss, MD11; Mitchell M. Levy, MD12; John C. Marshall, MD13; Greg S. Martin, MD, MSc14; Steven M. Opal, MD12; Gordon D. Rubenfeld, MD, MS15,16; Tom van der Poll, MD, PhD17; Jean-Louis Vincent, MD, PhD18; Derek C. Angus, MD, MPH19,20
JAMA. 2016;315(:801-810. doi:10.1001/jama.2016.0287.

Open access http://jama.jamanetwork.com/article.aspx?articleid=2492881

Oma zegt: Simpelheid troef!

Box 4.
qSOFA (Quick SOFA) Criteria
Respiratory rate ≥22/min

Altered mentation

Systolic blood pressure ≤100 mm Hg

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13 jarige dochter van anesthesioloog-intensivist/medical director HMC Ambulance Service (Qatar) heeft dringend hulp nodig:

Match4Zara @Match4Z

I urgently need a bone marrow transplant. I have a very rare tissue type due to mixed ethnicity (Arabic/British). Pls help me find a match

(meer dan 12.000 ReTweets)

Tot op heden is er geen match gevonden voor het meisje. Inmiddels is het in een aantal landen doorgedrongen dat dit probleem niet uniek is en er veel etinisch gemengde kinderen (halfbloedjes) overlijden omdat er geen match gevonden kan worden. Niet alleen Zara zoekt een match ook een zoontje van een brandweerman uit Londen is op zoek.

#Match4Tommy campaign launches to save life of firefighter's 4 year old boy
16 February 2016

Today we're backing an urgent appeal for more mixed raced donors as a London Firefighter’s son battles leukaemia.

Tommy Simpson is a 4 year old boy of White (British) and Black (Caribbean) heritage who loves nothing more than playing with his toy aeroplanes and putting on his Dad's uniform, pretending to be a firefighter.

In January 2016 he was diagnosed with Acute Myeloid Leukaemia (AML), after being admitted to hospital a few days before Christmas. He has been in hospital ever since.

Tommy's parents, London firefighter Nigel and Mary Kay Cosmetics Events Manager Maxine, have launched an urgent appeal to find Tommy a potential lifesaving stem cell donor in the event his imminent test results reveal he will require an unrelated stem cell (bone marrow) donor to save his life.

What can you do?

If you're White Northern European, Black African or Caribbean and mixed race, please become a donor on the stem cell register(opens in a new window).

You may potentially be able to save the life of a funny and beautiful little boy.

Less than 20 per cent chance

Tommy's mixed heritage makes it extremely hard to find a donor as matching stem cell tissue types are inherited.

Mixed race people like Tommy have less than a 20 per cent chance of finding an unrelated best possible match; as do individuals who are black or from a minority ethnic background.

There are only 3 per cent of donors on the UK stem cell register who are mixed race, making Tommy's chances of finding an unrelated donor extremely difficult.



Only child

Tommy, who is an only child, is currently being treated at London’s Great Ormond Street hospital. Extended family members were immediately tested, however a suitable match within the family was not found.

Nigel and Maxine, Tommy's parents, said: "Tommy doesn’t have any siblings so the one in four chance of a sibling being a match doesn't exist for Tommy.

"It is at best a 50 per cent chance for parents to be a match for their children; this is normally a route doctors go down when they can’t find anything better.

"We know the window of opportunity for an unrelated match being found is going fast with each day passing; that’s why we are appealing for people to join the stem cell register now."

Nigel's colleagues are showing their support for the #Match4Tommy campaign and the Brigade is using it's social media channels to help the appeal.

London Fire Commissioner Ron Dobson said: "Firefighter's are at the heart of our communities and help others day in day out to keep London safe.

"Now we need help from the public to respond to this urgent appeal for donors for a London firefighter’s son Tommy.

"If you are yet to join the stem cell registers, please attend this donor registration drive and encourage your family and friend to attend too; Tommy desperately needs your help."

African Caribbean Leukaemia Trust

Blood cancer charity ACLT (African Caribbean Leukaemia Trust) are leading the #Match4Tommy campaign by hosting donor registration drives to find an unrelated match for Tommy and the first donor drive for the #Match4Tommy appeal will be hosted by radio station Capital XTRA at their London Head Quarters - Global Radio, 30 Leicester Square, London WC2H 7LA on Saturday, 19 March, between 11am-6pm.

ACLT will be registering anyone in good health aged between 17-55. New registrants will complete a short application form and provide a cheek swab.

For more information on the #Match4Tommy donor drives, call ACLT on 020 3757 7700 or visit their website http://aclt.org/

http://www.london-fire.gov.uk/news/LatestNewsReleases_Match4Tommy.asp

In Qatar is besloten om het initiele initiatief van een aantal medewerkers van HMC om te zetten in een tijdelijk screeningcentrum en een nationaal stamcel programma. Een van de mobiele bloedbanken van HMC gaat gebruikt worden om zoveel mogelijk mensen te screenen.

Dr. Yousef al Maslamani, Medical Director at Hamad General Hospital (HGH), said:

The Interim Screening Center is laying the foundations as part of our preparations for establishing HMC’s own national blood stem cell program which will contribute to us continuing to delivering safe and effective care to all in Qatar.’

Dr. Yousef said the Interim Screening Center is also working with international organizations and clinicians to help find a match for 13-year-old Zara Al Shaikh, the daughter of Dr. Loua Al Shaikh, one of HMC’s senior physicians.

Dr. Al Shaikh has dedicated his life to saving lives in Qatar and we are honored to be playing a role in helping to find a life-saving donor match for his daughter.

http://marhaba.qa/hmc-opens-interim-blood-stem-cell-screening-centre/



Een mobiele bloedbank van HMC Qatar. De voertuigen vallen onder beheer van ambulancedienst (chauffeur + onderhoud + reiniging + aanvullen materialen). Iemand van ambulancedienst zorgt dat voertuig op afgesproken tijden op een locatie gereed staat, personeel van de bloedbank neemt het daarna over.

http://www.toutenkamion.com/en/mobile-units/blood-donation.html

[RAdeR]

https://www.youtube.com/watch?v=IZFYm-tS0io

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http://jama.jamanetwork.com/multimediaPlayer.aspx?mediaid=12511362

[RAdeR]

The researchers found that for the first 2 days after the daylight saving switch, the overall rate of ischemic stroke was 8% higher. After 2 days, the levels were back to normal.

[Kanarie]

Ik denk dan altijd: Zou dat ook gelden voor ploegendiensten en avondjes uit?

[RAdeR]

Uit een verwijzing in het onderzoek blijkt dat er relatie is dus slaap(problemen) en het risico op CVA

Greater sleep fragmentation was associated with a 27% higher chance of having severe arteriolosclerosis. For every additional two arousals per hour of sleep, there was a 30% higher chance of having visible signs of oxygen deprivation in the brain.

[Kanarie]

However, there are several ways to view these findings: sleep fragmentation may impair the circulation of blood to the brain, poor circulation of blood to the brain may cause sleep fragmentation, or both may be caused by another underlying risk factor."

Zelfde bron: http://www.medicalnewstoday.com/articles/305102.php

Note to self: Zoek de confounder!

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http://www.liveleak.com/view?i=6c9_1455806357